Defects or malfunctions in either the innate or adjustive immunologic response will provoke malady or illness. Such disorders area unit typically caused by Associate in Nursing hyperactive immunologic response (known as hypersensitivity reactions), Associate in Nursing inappropriate reaction to self (known as autoimmunity) or ineffective immune responses (known as immunodeficiency).

Hypersensitivity reactions  

Hypersensitivity reactions sit down with undesirable responses made by the traditional system. There are a unit four forms of hypersensitivity reactions:

·         Type I: immediate hypersensitivity.

·         Type II: cytotoxic or antibody-dependent hypersensitivity.

·         Type III: immune advanced illness.

.         Type IV: delayed-type hypersensitivity

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